Focusing on Distinctive Enzymes

Analysis of Nucleoside Analogs as Antimicrobials Focusing on Distinctive Enzymes in Borrelia burgdorferi

The primary line remedy for Lyme illness is remedy with doxycycline, amoxicillin, or cefuroxime. In endemic areas, the persistence of signs in lots of sufferers after completion of antibiotic remedy stays a serious healthcare concern.
The causative agent of Lyme illness is a

heavy metals and enzyme train in soils all through the zone of have an effect on of various

e auxotroph that can’t exist below free-living situations and relies upon upon the tick vector and mammalian hosts to satisfy its dietary wants.

Regardless of missing all main biosynthetic pathways, B. burgdorferi uniquely possesses three homologous and practical methylthioadenosine/S-adenosylhomocysteine nucleosidases (MTANs: Bgp, MtnN, and Pfs) concerned in methionine and purine salvage, underscoring the vital function these enzymes play within the life cycle of the spirochete.
At the very least one MTAN, Bgp, is outstanding in its presence on the floor of Lyme spirochetes and its twin performance in nutrient salvage and glycosaminoglycan binding concerned in host-cell adherence.
Thus, MTANs supply extremely promising targets for discovery of recent antimicrobials. Right here we report on our research to guage 5 nucleoside analogs for MTAN inhibitory exercise, and cytotoxic or cytostatic results on a bioluminescently engineered pressure of B. burgdorferi. All 5 compounds had been both alternate substrates and/or inhibitors of MTAN exercise, and diminished B. burgdorferi development.
Two inhibitors: 5′-deoxy-5′-iodoadenosine (IADO) and 5′-deoxy-5′-ethyl-immucillin A (dEt-ImmA) confirmed bactericidal exercise. Thus, these inhibitors exhibit excessive promise and kind the inspiration for improvement of novel and efficient antimicrobials to deal with Lyme illness.
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HSV-2 IgG ELISA Kit
E4682-100
EUR 539.00

Corticosterone Enzyme Immunoassay kit, 5 plates
K014-H5 5x96 well plate
EUR 1110.00

Cortisone Enzyme Immunoassay kit (One Plate)
K017-H1 1x96 well plate
EUR 370.00

Cortisone Enzyme Immunoassay kit (Five Plate)
K017-H5 5x96 well plate
EUR 1273.00

PGFM Enzyme Immunoassay kit (One Plate)
K022-H1 1x96 well plate
EUR 354.00

PGFM Enzyme Immunoassay kit (Five Plate)
K022-H5 5x96 well plate
EUR 664.00

RealScreen HSV-2 IgG ELISA Kit
EL022-096 96T
EUR 712.00

Cortisol Enzyme Immunoassay kit - 1 Strip plate
K003-H1 1x96 well plate
EUR 311.00

Cortisol Enzyme Immunoassay kit - 1 Whole plate
K003-H1W 1x96 well plate
EUR 305.00

Cortisol Enzyme Immunoassay kit - 5 Strip plates
K003-H5 5x96 well plate
EUR 1055.00

Cortisol Enzyme Immunoassay kit - 5 Whole plates
K003-H5W 5x96 well plate
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Human IgG AssayLite Fluorescent Immunoassay Kit
FEI7200 96 Well Plate
EUR 396.00

LH (Luteinizing Hormone) ELISA test
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HSV-1 IgG ELISA Kit
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HSV-?(Herpes Simplex Virus ?AntibodyIgM) ELISA test
37 96T/Box Ask for price
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Human HSV-2 IgG ELISA Kit (Direct EIA)
EK7060 96wells/kit, with removable strips.
EUR 478.00

Accu-Tell COVID-19 IgG/IgM Rapid Test
GEN-B352-20tests 20 tests
EUR 236.00
Description: A rapid test for detection of antibodies (IgG and IgM) for 2019-nCoV, the novel Coronavirus from the Wuhan strain. The test is easy to perform, takes 10 minutes to provide reliable results and is higly specific to the 2019-nCoV Coronavirus.

Accu-Tell COVID-19 IgG/IgM Rapid Test
GEN-B352-40tests 40 tests
EUR 321.00
Description: A rapid test for detection of antibodies (IgG and IgM) for 2019-nCoV, the novel Coronavirus from the Wuhan strain. The test is easy to perform, takes 10 minutes to provide reliable results and is higly specific to the 2019-nCoV Coronavirus.

Human Estrone-3-Glucuronide (E1G)Enzyme Immunoassay ELISA Kit
QY-E05423 96T
EUR 361.00

NATtrol Zika Virus Stock (Qualitative) (1 mL)
TEST 1 mL
EUR 1106.64
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RealScreen HSV-1 IgG ELISA Kit
EL020-096 96T
EUR 712.00

HSV-?(Herpes Simplex Virus ?Antibody IgM) ELISA test
35 96T/Box Ask for price
  • Area of application: Prepotency testing
Description: ELISA based test for quantitative detection of HSV-?(Herpes Simplex Virus ?Antibody IgM)

HDV-IgG hepatitis D IgG ELISA test
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  • Area of application: Hepatitis testing
Description: ELISA based test for quantitative detection of HDV-IgG hepatitis D IgG

Ibrutinib drug-Human IgG Conjugate
IBT17-IgG 100 ug
EUR 529.00

Human Toxoplasma (TOX) IgG Rapid Test Kit
abx092098-20tests 20 tests
EUR 217.00
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COVID-19 IgG/IgM Rapid Test Kit
UNCOV-20 20T/kit
EUR 155.00

2019-nCoV IgG/IgM Rapid Test Cassette (Whole Blood/Serum/Plasma)
GEN-402-25tests 25 tests
EUR 244.00
Description: A rapid test for detection of antibodies (IgG and IgM) for 2019-nCoV, the novel Coronavirus from the Wuhan strain. The test is easy to perform, takes 10 minutes to provide reliable results and is higly specific to the 2019-nCoV Coronavirus.

Immunoassay Stabilizer
85R-103 1 liter
EUR 481.00
Description: Stabilizing buffer for use in immunoassays

Human Anti-Herpes Simplex Virus 2 IgG (HSV-2 IgG) ELISA kit, 96 tests, Quantitative
3300-390-H2G 1 kit
EUR 590.00

Human Cytomegalovirus Antibody IgG (Anti-CMV IgG) Rapid Test Kit
abx092099-20tests 20 tests
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HEV-IgG CE Hepatitis E IgG ELISA test
91 96T/Box Ask for price
  • Area of application: Hepatitis testing
Description: ELISA based test for quantitative detection of HEV-IgG CE Hepatitis E IgG

Human Cytomegalovirus IgG / IgM, Toxoplasma IgG / IgM, Rubella IgG Rapid Test Kit
abx092078-20tests 20 tests
EUR 342.00
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HSV Grade 2
DAG-H10363 1 ml dry ice
EUR 1105.00

11,12-DHET Immunoassay Kit
DH4 1 Kit
EUR 307.00

Cystatin C Immunoassay Kit
K012-H1 1x96 well plate
EUR 405.00

Human IgA, IgG and IgM AssayLite Multiplex Fluorescent Immunoassay Kit
FI700161M3 96 Well Plate
EUR 1227.00

Human HSV-1 IgG ELISA Kit (Direct EIA)
EK7058 96wells/kit, with removable strips.
EUR 478.00

HSV-2 IgM ELISA Kit
E4683-100
EUR 539.00

RV (Rubella Antibody IgG) ELISA test
30 96T/Box Ask for price
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Description: ELISA based test for quantitative detection of RV (Rubella Antibody IgG)

CMV (Cytomegalovirus Antibody IgG) ELISA test
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TOX (Toxoplasma Antibody IgG) ELISA test
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ANA (Antinuclear Antibody IgG) ELISA test
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Description: ELISA based test for quantitative detection of ANA (Antinuclear Antibody IgG)

ACA (Anticardiolipin Antibody IgG) ELISA test
59 96T/Box Ask for price
  • Area of application: Immunological infertility
Description: ELISA based test for quantitative detection of ACA (Anticardiolipin Antibody IgG)

Human Hepatitis A Virus IgG Rapid Test Kit
abx092012-25tests 25 tests
EUR 425.00
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Human Chlamydia Pneumoniae (CP) IgG Rapid Test Kit
abx092079-20tests 20 tests
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Human Mycoplasma Pneumoniae (MP) IgG Rapid Test Kit
abx092081-20tests 20 tests
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Human Mycobacterium Tuberculosis (MT) IgG Rapid Test Kit
abx092084-20tests 20 tests
EUR 230.00
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Human Helicobacter Pylori (HP) IgG Rapid Test Kit
abx092090-20tests 20 tests
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Human Hantavirus (HV) IgM / IgG Rapid Test Kit
abx092094-20tests 20 tests
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Human Rubella Virus (RV) IgG Rapid Test Kit
abx092097-20tests 20 tests
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Human Rabies Virus (HRV) IgG Rapid Test Kit
abx092100-20tests 20 tests
EUR 342.00
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Human ACE2(Angiotensin-converting enzyme 2) ELISA Kit
EH0027 96T
EUR 524.10
  • Detection range: 0.391-25 ng/ml
  • Uniprot ID: Q9BYF1
  • Alias: ACEH/ACEII
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.234 ng/ml

Rat Ace2(Angiotensin-converting enzyme 2) ELISA Kit
ER0609 96T
EUR 567.60
  • Detection range: 0.156-10 ng/ml
  • Uniprot ID: Q5EGZ1
  • Alias: Ace2/ACE-related carboxypeptidase/
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 0.094 ng/ml

Anti-Glycoprotein B (HSV-1/HSV-2) Purified
11-330-C025 0.025 mg
EUR 90.00

Anti-Glycoprotein B (HSV-1/HSV-2) Purified
11-330-C100 0.1 mg
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Human Anti-Herpes Simplex Virus 1+2 IgG (HSV-1/2 IgG) ELISA kit, 96 tests, Quantitative
3300-400-12G 1 kit
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CaspSELECT Caspase 3 Immunoassay Kit
55R-1338 100 assays
EUR 1022.00
Description: Assay Kit for detection of Capase 3 activity in the research laboratory

cAMP Direct Immunoassay Kit (Colorimetric)
K2044-100 100 assays
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cGMP Direct Immunoassay Kit (Colorimetric)
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EUR 529.00

cAMP Direct Immunoassay Kit (Colorimetric)
K371-100
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cGMP Direct Immunoassay Kit (Colorimetric)
K372-100
EUR 512.00

QuickTiter Adenovirus Titer Immunoassay Kit
VPK-109 100 assays
EUR 705.00
Description: Accurate measurement of adenovirus titer is critical for gene delivery. Traditional plaque-forming unit (PFU) assays are long and suffer from high inter-assay variability. The QuickTiter Adenovirus Titer Immunoassay Kit provide a quick, complete system to functionally titer virus infectivity. The assay recognizes all 41 serotypes of adenovirus, and can be used with any adenovirus system that can amplify in HEK 293 cells.

Bovine Immunoglobulin G (IgG) ELISA Kit
DLR-IgG-b-48T 48T
EUR 456.00
  • Should the Bovine Immunoglobulin G (IgG) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Bovine Immunoglobulin G (IgG) in samples from serum, plasma or other biological fluids.

Bovine Immunoglobulin G (IgG) ELISA Kit
DLR-IgG-b-96T 96T
EUR 590.00
  • Should the Bovine Immunoglobulin G (IgG) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Bovine Immunoglobulin G (IgG) in samples from serum, plasma or other biological fluids.

Canine Immunoglobulin G (IgG) ELISA Kit
DLR-IgG-c-48T 48T
EUR 441.00
  • Should the Canine Immunoglobulin G (IgG) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Canine Immunoglobulin G (IgG) in samples from serum, plasma or other biological fluids.

Canine Immunoglobulin G (IgG) ELISA Kit
DLR-IgG-c-96T 96T
EUR 570.00
  • Should the Canine Immunoglobulin G (IgG) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Canine Immunoglobulin G (IgG) in samples from serum, plasma or other biological fluids.

Equine Immunoglobulin G (IgG) ELISA Kit
DLR-IgG-Eq-48T 48T
EUR 360.00
  • Should the Equine Immunoglobulin G (IgG) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Equine Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Equine Immunoglobulin G (IgG) ELISA Kit
DLR-IgG-Eq-96T 96T
EUR 457.00
  • Should the Equine Immunoglobulin G (IgG) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Equine Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Goat Immunoglobulin G (IgG) ELISA Kit
DLR-IgG-g-48T 48T
EUR 464.00
  • Should the Goat Immunoglobulin G (IgG) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Goat Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Goat Immunoglobulin G (IgG) ELISA Kit
DLR-IgG-g-96T 96T
EUR 601.00
  • Should the Goat Immunoglobulin G (IgG) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Goat Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Immunoglobulin G (IgG) ELISA Kit
DLR-IgG-Hu-48T 48T
EUR 239.00
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Description: A competitive inhibition quantitative ELISA assay kit for detection of Human Immunoglobulin G (IgG) in samples from serum, plasma or other biological fluids.

Human Immunoglobulin G (IgG) ELISA Kit
DLR-IgG-Hu-96T 96T
EUR 292.00
  • Should the Human Immunoglobulin G (IgG) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Human Immunoglobulin G (IgG) in samples from serum, plasma or other biological fluids.

Mouse Immunoglobulin G (IgG) ELISA Kit
DLR-IgG-Mu-48T 48T
EUR 328.00
  • Should the Mouse Immunoglobulin G (IgG) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Mouse Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse Immunoglobulin G (IgG) ELISA Kit
DLR-IgG-Mu-96T 96T
EUR 415.00
  • Should the Mouse Immunoglobulin G (IgG) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Mouse Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Porcine Immunoglobulin G (IgG) ELISA Kit
DLR-IgG-p-48T 48T
EUR 456.00
  • Should the Porcine Immunoglobulin G (IgG) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Porcine Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates or other biological fluids.

Porcine Immunoglobulin G (IgG) ELISA Kit
DLR-IgG-p-96T 96T
EUR 590.00
  • Should the Porcine Immunoglobulin G (IgG) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Porcine Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates or other biological fluids.

Rat Immunoglobulin G (IgG) ELISA Kit
DLR-IgG-Ra-48T 48T
EUR 334.00
  • Should the Rat Immunoglobulin G (IgG) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Rat Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rat Immunoglobulin G (IgG) ELISA Kit
DLR-IgG-Ra-96T 96T
EUR 422.00
  • Should the Rat Immunoglobulin G (IgG) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Rat Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rabbit Immunoglobulin G (IgG) ELISA Kit
DLR-IgG-Rb-48T 48T
EUR 337.00
  • Should the Rabbit Immunoglobulin G (IgG) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Rabbit Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rabbit Immunoglobulin G (IgG) ELISA Kit
DLR-IgG-Rb-96T 96T
EUR 426.00
  • Should the Rabbit Immunoglobulin G (IgG) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Rabbit Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Bovine Immunoglobulin G (IgG) ELISA Kit
RDR-IgG-b-48Tests 48 Tests
EUR 473.00

Bovine Immunoglobulin G (IgG) ELISA Kit
RDR-IgG-b-96Tests 96 Tests
EUR 654.00

A Perspective on Enzyme Inhibitors from Marine Organisms

Marine habitats are promising sources for the identification of novel organisms in addition to pure merchandise. Nonetheless, we lack detailed data on a lot of the marine biosphere. Within the final decade, quite a lot of experiences described the potential of figuring out novel bioactive compounds or secondary metabolites from marine environments.
That is, and might be, a promising supply for candidate compounds in pharma analysis and chemical biology. Lately, a variety of novel methods had been launched into the sphere, and it has turn out to be simpler to truly prospect for pure merchandise, equivalent to enzyme inhibitors. These novel compounds then must be characterised and evaluated compared to well-known representatives.
A variety of present analysis tasks goal the exploitation of marine organisms and thus the corresponding range of metabolites. These are sometimes encountered as potential medicine or organic energetic compounds. Amongst these, the category of enzyme inhibitors is a crucial group of compounds. There’s room for brand spanking new discoveries, and a few more moderen discoveries are highlighted herein.

World evaluation of adenylate-forming enzymes reveals β-lactone biosynthesis pathway in pathogenic Nocardia

Enzymes that cleave ATP to activate carboxylic acids play important roles in major and secondary metabolism in all domains of life. Class I adenylate-forming enzymes share a conserved structural fold however act on a variety of substrates to catalyze reactions concerned in bioluminescence, nonribosomal peptide biosynthesis, fatty acid activation, and β-lactone formation.
Regardless of their metabolic significance, the substrates and features of the overwhelming majority of adenylate-forming enzymes are unknown with out instruments out there to precisely predict them. Given the essential roles of adenylate-forming enzymes in biosynthesis, this additionally severely limits our capacity to foretell pure product buildings from biosynthetic gene clusters.
Right here we used machine studying to foretell adenylate-forming enzyme operate and substrate specificity from protein sequences. We constructed a web-based predictive instrument and used it to comprehensively map the biochemical range of adenylate-forming enzymes throughout >50,000 candidate biosynthetic gene clusters in bacterial, fungal, and plant genomes.
Ancestral phylogenetic reconstruction and sequence similarity networking of enzymes from these clusters prompt divergent evolution of the adenylate-forming superfamily from a core enzyme scaffold most associated to modern CoA ligases in direction of extra specialised features together with β-lactone synthetases.
Our classifier predicted β-lactone synthetases in uncharacterized biosynthetic gene clusters conserved in >90 completely different strains of Nocardia To check our prediction, we purified a candidate β-lactone synthetase from Nocardia brasiliensis and reconstituted the biosynthetic pathway in vitro to hyperlink the gene cluster to the β-lactone pure product, nocardiolactone. We anticipate our machine studying method will support in practical classification of enzymes and advance pure product discovery.

Dipeptidyl-Peptidase 4 Enzyme
abx073761-10ng 10 ng
EUR 328.00
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Dipeptidyl-Peptidase 4 Enzyme
abx073761-2ng 2 ng
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Dipeptidyl-Peptidase 4 Enzyme
abx073761-700ng 700 ng
EUR 6397.00
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IL-4 Interleukin 4 Human Recombinant Protein, Yeast
PROTP05112-4 Regular: 10ug
EUR 317.00
Description: Interleukin-4 Human Recombinant produced in yeast is a single, glycosylated polypeptide chain containing 129 amino acids.;The IL-4 is purified by proprietary chromatographic techniques.

Co-1686
20-abx183952
  • EUR 356.00
  • EUR 523.00
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Co 102862
B7135-10 10 mg
EUR 276.00

Co 102862
B7135-50 50 mg
EUR 999.00

Individual Reaction Mix 4
G065-4 200 reactions
EUR 167.00

Human Lactate Dehydrogenase 4 Enzyme
abx070017-100Units 100 Units
EUR 1191.00
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DNA Polymerase Enzyme (4 kb)
abx071004-10kU 10 kU
EUR 384.00
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DNA Polymerase Enzyme (4 kb)
abx071004-3kU 3 kU
EUR 230.00
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DNA Polymerase Enzyme (4 kb)
abx071004-500U 500 U
EUR 175.00
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DNA Polymerase Enzyme (4 kb)
abx071004-50kU 50 kU
EUR 1052.00
  • Shipped within 5-10 working days.

Colorectal Cancer Exosome
P141-CO NULL
EUR NULL

Colorectal Cancer Exosome RNA
P241-CO NULL
EUR NULL

pBbA5c-MevT(CO)-T1-MBIS(CO, ispA)
PVT17450 2 ug
EUR 300.00

Frit Kit
FRIT-KIT 1each
EUR 124.00
Description: Kit to create frits in capillaries. Includes formamide, Kasil-1, Kasil-1624 and a cleaving tool.

pLenti-CLDN1 shRNA-4 Plasmid
PVTBAV04867-4 2 ug
EUR 356.00

Feline IL-4 Recombinant Protein
R00230-4 5ug/vial
EUR 259.00
Description: IL-4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of CD4+ T-cells into Th2 cells. It is a key regulator in humoral and adaptive immunity. Feline IL-4 Recombinant Protein is purified interleukin-4 produced in yeast.

Column Packing Kit
PACK-KIT 1pack
EUR 1035.00
Description: Column packing kit for pressure cells. Includes: HPREG regulator, TBNG10 tubing, CAP-75 capillary, and STRB5X2 stir bar.

Recombinant Human Tumor Necrosis Factor Receptor Type 4
CC136-101 1mg
EUR 10310.00

PCR Mycoplasma Detection Kit
M034-Kit Kit
EUR 266.00

Recombinant Human sTNF Receptor Type II Protein
PROTP20333-4 20ug
EUR 317.00
Description: TNFRII is a member of the TNFR family of transmembrane proteins, and is expressed in immune cells and certain endothelial cells. It is a high affinity receptor for TNF-α but manifests a lower affinity to TNF-β. Signaling through this receptor regulates various biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, coagulation, and neurotransmission. Soluble TNFRII is capable of inhibiting TNF-α induced activities by acting as a decoy receptor. Recombinant human sTNFRII is an 18.9 kDa protein (174 amino acid residues) comprising the cysteine rich ligand binding portion of the extracellular domain of the TNFRII protein.

DIGITAL SHAKER FOR 4 MICROPLATES, 120V
6780-4 1/pk
EUR 798.00
Description: Lab Equipment; Shakers & Mixers

Mouse FibrOut 4, for brain, neural
4-20507 1 ml Ask for price

Mouse FibrOut 4, for brain, neural
4-20508 5 x 1 ml Ask for price

Rat FibrOut 4, for brain, neural
4-20533 1 ml Ask for price

Rat FibrOut 4, for brain, neural
4-20534 5 x 1 ml Ask for price

Human FibrOut 4, for brain, neural
4-21552 1 ml Ask for price

Human FibrOut 4, for brain, neural
4-21553 5 x 1 ml Ask for price

Recombinant Human 4-1BB Receptor Protein
PROTQ07011-4 20ug
EUR 317.00
Description: 4-1BB Receptor, a member of the TNF superfamily of receptors, is mainly expressed on the surface of a variety of T cells, but also found in B cells, monocytes, and various transformed cell lines. 4-1BB Receptor binds to 4-1BBL to provide a co-stimulatory signal for T lymphocytes. Signaling by 4-1BB Receptor has been implicated in the antigen-presentation process and generation of cytotoxic T cells. The human 4-1BB Receptor gene codes for a 255 amino acid type I transmembrane protein containing a 17 amino acid N-terminal signal sequence, a 169 amino acid extracellular domain, a 27 amino acid transmembrane domain and a 42 amino acid cytoplasmic domain. Recombinant human soluble 4-1BB Receptor is a 167 amino acid polypeptide (17.7 kDa), which contains the cysteine rich TNFR-like extracellular domain of 4-1BB Receptor.

Recombinant Human PF-4 (CXCL4) Protein
PROTP02776-4 20ug
EUR 317.00
Description: PF-4 is a CXC chemokine that is expressed in megakaryocytes and stored in the α-granules of platelets. PF-4 is chemotactic towards neutrophils and monocytes and has been shown to inhibit angiogenesis. Recombinant human PF-4 is a 7.8 kDa protein containing 70 amino acid residues, including the four highly conserved residues present in CXC chemokines.

CO-1686 (Rociletinib)
2794-25
EUR 675.00

CO-1686 (Rociletinib)
2794-5
EUR 207.00

Co 101244 hydrochloride
B7062-10 10 mg
EUR 334.00

Co 101244 hydrochloride
B7062-50 50 mg
EUR 1243.00

Co-Precipitant, Pink
BIO-37075 1.5ml, 5mg/ml Ask for price

Lung Dissociation System 8 (Alveolar type II), Rat
4-20318 ea Ask for price

Bone Dissociation System 4 (Osteoblasts), Adult Mouse
4-20214 ea Ask for price

Liver Dissociation System 4 (Hepatocytes, rat), Rat
4-20304 ea Ask for price

Pituitary Dissociation System 4 (Pituitary), Adult mouse
4-20404 ea Ask for price

Thymus Dissociation System 4 (Epithelial), Adult rat
4-20444 ea Ask for price

StemBoost? Growth Factor Set V
K881-4
EUR 697.00

StemBoost? Growth Factor Set VII
K883-4
EUR 697.00

Cas9 Protein and T7 gRNA SmartNuclease Synthesis Kit
CAS400A-KIT 1 kit (10 rxn)
EUR 1110.00
  • Category: Cas9

Human Peroxisomal Multifunctional Enzyme Type 2 (HSD17B4) ELISA Kit
abx387893-96tests 96 tests
EUR 911.00
  • Shipped within 5-12 working days.

CMV-hspCas9-T2A-Puro SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit
CASLV100PA-KIT 1 Kit
EUR 1132.00
  • Category: Cas9

CMV-hspCas9-EF1-GFP SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit
CASLV105PA-KIT 1 Kit
EUR 1132.00
  • Category: Cas9

MSCV-hspCas9-T2A-Puro SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit
CASLV120PA-KIT 1 Kit
EUR 1132.00
  • Category: Cas9

MSCV-hspCas9-EF1-GFP SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit
CASLV125PA-KIT 1 Kit
EUR 1132.00
  • Category: Cas9

DIGITAL SHAKER FOR 4 MICROPLATES, 230V-EU PLUG
6781-4 1/pk
EUR 798.00
Description: Lab Equipment; Shakers & Mixers

DIGITAL SHAKER FOR 4 MICROPLATES, 230V-UK PLUG
6782-4 1/pk
EUR 798.00
Description: Lab Equipment; Shakers & Mixers

Cartilage Dissociation System 4 (Chondrocytes), Mouse and Rat
4-20234 ea Ask for price

Mammary Dissociation System 4 (Epithelial, Swiss 3T3), Mouse
4-20324 ea Ask for price

Pancreas Dissociation System 4 (Islets), Mouse and Rat
4-20374 ea Ask for price

Skin Dissociation System 4 (Keratinocytes), Mouse and Rat
4-20434 ea Ask for price

Multiplex gRNA Kit + EF1-T7-hspCas9-H1-gRNA linearized SmartNuclease vector
CAS700A-KIT 10 rxn
EUR 1132.00
  • Category: Cas9

Multiplex gRNA Kit + CAG-T7-hspCas9-H1-gRNA linearized SmartNuclease vector
CAS720A-KIT 10 rxn
EUR 1132.00
  • Category: Cas9

Multiplex gRNA Kit + CMV-T7-hspCas9-H1-gRNA linearized SmartNuclease vector
CAS740A-KIT 10 rxn
EUR 1132.00
  • Category: Cas9

Dengue virus type 4 PCR kit
PCR-H524-48R 50T
EUR 524.40
  • Contact us in order to know the reactivity of the kit.
Description: An conventional PCR kit for detection of Dengue virus type 4

Dengue virus type 4 PCR kit
PCR-H524-96R 100T
EUR 669.40
  • Contact us in order to know the reactivity of the kit.
Description: An conventional PCR kit for detection of Dengue virus type 4

Human Peroxisomal multifunctional enzyme type 2 (HSD17B4)
1-CSB-YP010774HU
  • EUR 430.00
  • EUR 234.00
  • EUR 1508.00
  • EUR 642.00
  • EUR 1009.00
  • EUR 291.00
  • 0
  • 1
  • 2
  • 3
  • 4
  • 5
  • MW: 81.7 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Human Peroxisomal multifunctional enzyme type 2(HSD17B4) expressed in Yeast

Peroxisomal Multifunctional Enzyme Type 2 (HSD17B4) Antibody
abx026859-400ul 400 ul
EUR 523.00
  • Shipped within 5-10 working days.

Peroxisomal Multifunctional Enzyme Type 2 (HSD17B4) Antibody
abx026859-80l 80 µl
EUR 286.00
  • Shipped within 5-10 working days.

Peroxisomal Multifunctional Enzyme Type 2 (HSD17B4) Antibody
20-abx004727
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 0
  • 1
  • 2
  • 3
  • Shipped within 5-10 working days.

Peroxisomal Multifunctional Enzyme Type 2 (HSD17B4) Antibody
abx216048-100ug 100 ug
EUR 439.00
  • Shipped within 5-10 working days.

Peroxisomal Multifunctional Enzyme Type 2 (HSD17B4) Antibody
20-abx113089
  • EUR 732.00
  • EUR 398.00
  • 0
  • 1
  • Shipped within 5-10 working days.

Peroxisomal Multifunctional Enzyme Type 2 (HSD17B4) Antibody
20-abx121133
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 0
  • 1
  • 2
  • Shipped within 5-10 working days.

Peroxisomal Multifunctional Enzyme Type 2 (HSD17B4) Antibody
20-abx242132
  • EUR 411.00
  • EUR 300.00
  • 0
  • 1
  • Shipped within 5-10 working days.

Peroxisomal Multifunctional Enzyme Type 2 (HSD17B4) Antibody
20-abx242133
  • EUR 411.00
  • EUR 300.00
  • 0
  • 1
  • Shipped within 5-10 working days.

Peroxisomal Multifunctional Enzyme Type 2 (HSD17B4) Antibody
20-abx320221
  • EUR 300.00
  • EUR 244.00
  • 0
  • 1
  • Shipped within 5-10 working days.

Peroxisomal Multifunctional Enzyme Type 2 (HSD17B4) Antibody
abx234026-100ug 100 ug
EUR 481.00
  • Shipped within 5-12 working days.

Peroxisomal Multifunctional Enzyme Type 2 (HSD17B4) Antibody
20-abx327690
  • EUR 314.00
  • EUR 244.00
  • 0
  • 1
  • Shipped within 5-10 working days.

Peroxisomal Multifunctional Enzyme Type 2 (HSD17B4) Antibody
20-abx322147
  • EUR 300.00
  • EUR 244.00
  • 0
  • 1
  • Shipped within 5-10 working days.

T7 gRNA SmartNuclease Synthesis Kit (includes CAS510A-1 & T7 IVT synthesis reagents)
CAS510A-KIT 1 Kit
EUR 805.00
  • Category: Cas9

Human Carbohydrate Antigen 72-4 (CA72-4) ELISA Kit
DLR-CA72-4-Hu-48T 48T
EUR 479.00
  • Should the Human Carbohydrate Antigen 72-4 (CA72-4) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Carbohydrate Antigen 72-4 (CA72-4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Carbohydrate Antigen 72-4 (CA72-4) ELISA Kit
DLR-CA72-4-Hu-96T 96T
EUR 621.00
  • Should the Human Carbohydrate Antigen 72-4 (CA72-4) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Carbohydrate Antigen 72-4 (CA72-4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Carbohydrate Antigen 72-4 (CA72-4) ELISA Kit
RDR-CA72-4-Hu-48Tests 48 Tests
EUR 500.00

Human Carbohydrate Antigen 72-4 (CA72-4) ELISA Kit
RDR-CA72-4-Hu-96Tests 96 Tests
EUR 692.00

Human Carbohydrate Antigen 72-4 (CA72-4) ELISA Kit
RD-CA72-4-Hu-48Tests 48 Tests
EUR 478.00

Human Carbohydrate Antigen 72-4 (CA72-4) ELISA Kit
RD-CA72-4-Hu-96Tests 96 Tests
EUR 662.00

Cas9 Nickase: CMV-hspCas9(D10A)-T2A-Puro SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit
CASLV200PA-KIT 1 Kit
EUR 1132.00
  • Category: Cas9

Cas9 Nickase: CMV-hspCas9(D10A)-EF1-GFP SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit
CASLV205PA-KIT 1 Kit
EUR 1132.00
  • Category: Cas9

Cas9 Nickase: MSCV-hspCas9(D10A)-T2A-Puro SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit
CASLV220PA-KIT 1 Kit
EUR 1132.00
  • Category: Cas9
April 2021
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